In a major development a single-use device and therapy could mean a major development in the treatment of pain and function associated with knee osteoarthritis. The SVF-2 uniquely harvests, isolates, and reimplants stromal progenitor cells to help control pain, reduce inflammation and repair inflamed tissue in the knee. FDA compliant clinical trials for this no-joint-surgery, minimally invasive option have shown no serious adverse events and significant improvements in pain, stiffness and function.